The SULF2 Antibody (C-term) from MyBioSource.com is a Rabbit Polyclonal antibody to SULF2, and Sulfatase 2. This antibody recognizes Human antigen. The SULF2 Antibody (C-term) has been validated for the following applications: ELISA, and Western Blot.
Description
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265])